Necrostatin-1

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Cat No.

CEI-0581

Description

Inhibits necroptosis, a non-apoptotic cell death pathway. Does not inhibit FAS-induced apoptosis and has no effect on apoptotic morphology. Inhibits RIP1 kinase, the key upstream kinase involved in the activation of necroptosis (EC₅₀ = 180 nM)

Alias

Methylthiohydantoin-DL-tryptophan; Nec-1

Appearance

White solid

Product Overview

A necroptosis inhibitor

CAS_No

4311-88-0

Molecular Weight

333.34

Purity

>97% by elemental analysis

Storage

-20 centigrade

Synonyms

Methylthiohydantoin-DL-tryptophan; Nec-1

Targets

Necroptosis

Molecular Formula

C₁₃H₁₃N₃OS

Chemical Name

5-(1H-Indol-3-ylmethyl)-3-methyl-2-thioxo-4-imidazolidinone

Solubility

Water

Shipping Conditions

Gel pack

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Project Description:

For research and industrial use only, not for personal medicinal use.

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