Necrostatin-5

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Cat No.

CEI-0585

Description

Inhibits non-apoptotic cell death pathway by inhibition of the death domain receptor-associated adaptor kinase RIP1. Three distinct mechanisms appear to be involved in necroptosis, the alternative active cell death pathway: T-loop dependent inhibition by necrostatin-1; partially T-loop independent inhibition by necrostatin-3 and indirect inhibition of RIP1 by necrostatin-5

Alias

Nec-5

Appearance

Brown solid

Product Overview

A necroptosis inhibitor

CAS_No

337349-54-9

Molecular Weight

592.42

Purity

>98% by NMR

Storage

-20 centigrade

Synonyms

Nec-5

Targets

Necroptosis, Necrosis

Molecular Formula

C₁₉H₁₇N₃O₂S₂

Chemical Name

3-p-Methoxyphenyl-5,6-tetramethylenothieno[2,3-d]pyrimidin-4-one-2-mercaptoethylcyanide

Solubility

DMSO or Ethanol or water

Shipping Conditions

Gel pack

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Project Description:

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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