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Neuraminidase from Microorganism

Cat No.
NATE-1716
Description
Neuraminidase enzymes are glycoside hydrolase enzymes (EC 3.2.1.18) that cleave the glycosidic linkages of neuraminic acids. Neuraminidase enzymes are a large family, found in a range of organisms. The best-known neuraminidase is the viral neuraminidase, a drug target for the prevention of the spread of influenza infection. The viral neuraminidases are frequently used as antigenic determinants found on the surface of the Influenza virus. Some variants of the influenza neuraminidase confer more virulence to the virus than others. Other homologs are found in mammalian cells, which have a range of functions.
Abbr
NRH (Microorganism)
Source
Microorganism
Form
White powder, lyophilized
Enzyme Commission Number
EC 3.2.1.18
Activity
>300U/mg protein
CAS No.
9001-67-6
Molecular Weight
52 kDa (SDS-PAGE)
Isoelectric point
5.86
pH Stability
4.0~10.0 (25℃, 25hr)
Michaelis Constant
1.02 mM (sialyllactose pH6.5)
Unit Definition
One unit will deaminated one micromole of NAcetylneuraminy-R to N-Actylneuraminate per minute at pH 7.5 at 37℃.
Optimum pH
5
Optimum temperature
50℃
Thermal stability
< 40℃ (pH 7.5, 10min)
Storage
Store at -20°C.
Inhibitors
Ag+, Hg2+
Synonyms
sialidase; α-neuraminidase; acetylneuraminidase; exo-α-sialidase; EC 3.2.1.18; 9001-67-6
Notes
INTENDED FOR RESEARCH USE ONLY, NOT FOR USE IN HUMAN, THERAPEUTIC OR DIAGNOSTIC APPLICATIONS.

"Neuraminidase" Total Products Page

Catalog Product Name EC No. CAS No. Source Price
NATE-1683 Neuraminidase, recombinant EC 3.2.1.18 9001-67-6 Inquiry
NATE-0479 Native Clostridium perfringens (C. welchii) Neuraminidase Agarose EC 3.2.1.18 9001-67-6 Clostridium perfringens (C. welchii) Inquiry
NATE-0480 Native Clostridium perfringens (C. welchii) Neuraminidase EC 3.2.1.18 Clostridium perfringens (C. welchii) Inquiry
NATE-0481 Native Vibrio cholerae Neuraminidase EC 3.2.1.18 9001-67-6 Vibrio cholerae Inquiry
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