Nodularin

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Cat No.

CEI-0632

Description

Nodularin is a hepatotoxic monocylic pentapeptide produced by cyanobacterium Nodularia spumigena. It is a potent inhibitor of protein phosphatase types 1 (PP1) and 2A (PP2A), exhibiting IC 50 values of 1.8 and 0.026 nM, respectively. It inhibits PP2B only at higher concentrations (IC 50 = 1.8 µM).

Appearance

White solid

Product Overview

A potent inhibitor of protein phosphatase types 1 (PP1) and 2A (PP2A)

CAS_No

118399-22-7

Molecular Weight

810.45

Purity

>98%

Storage

-20 centigrade

Targets

PPP1CA, PPP2R4

Molecular Formula

C41H60N8O10

Chemical Name

Cyclo[3S-amino-9S-methoxy-2S,6E,8S-trimethyl-10-phenyl-4,6- decadienoyl-D-γ-glutamyl-(2Z)-2-(methylamino)-2-butenoyl-(3S)- 3-methyl-D-β-aspartyl-L-arginyl]

Solubility

DMSO (25 mg/ml) or EtOH (25 mg/ml)

Shipping Conditions

Gel pack

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Project Description:

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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