Panobinostat (LBH589)

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Cat No.

CEI-0499

Description

(LBH589) is a highly potent inhibitor of both histone deacetylase 1 (HDAC1) activity and tumour cell proliferation in vitro. The IC₅₀ values of HDAC isozymes HDAC1-IP Ac-H4, HDAC8, MALunselective, B61HDAC1 and B12HDAC6 are 0.23±0.06, 283±29, 75±4, 47±5 and 89±12 nM, respectively. And to A2780 proliferation, IC₅₀ value is 4.6±1.8 nM.

Alias

LBH589, LBN-589, NVP-LBH590

Appearance

White solid

Product Overview

A HDAC inhibitor

CAS_No

404950-80-7

Molecular Weight

371.27

Purity

>98% by HPLC

Storage

-20 centigrade

Synonyms

LBH589, LBN-589, NVP-LBH590

Targets

HDAC

Molecular Formula

C₂₁H₂₃N₃O₂

Solubility

DMSO (~100 mM) or EtOH (~ 100 mM)

Shipping Conditions

Gel pack

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Project Description:

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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