PD173955

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Cat No.

CEI-1099

Description

PD173955 is an ATP-competitive, dual Src/Abl kinase inhibitor. It is a potent inhibitor of Bcr-Abl with an IC50 of 1-2 nM in kinase inhibition assays. In cellular growth assays it inhibits Bcr-Abl-dependent substrate tyrosine phosphorylation. PD173955 al

Abbr

PD173955(BCR, ABL1, SRC)

Alias

ALL, BCR1, CML, D22S11, D22S662, PHL

Product Overview

ATP-competitive, dual Src/Abl kinase inhibitor

CAS_No

260415-63-2

Molecular Weight

443.35

Purity

> 95%

Stability

2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO

Storage

4 centigrade

Synonyms

ALL, BCR1, CML, D22S11, D22S662, PHL

Targets

Bcr-Abl, c-Src

IC50

2-35

Molecular Formula

C21H16Cl2N4OS

Chemical Name

6-(2,6-dichlorophenyl)-8-methyl-2-(3-(methylthio)phenylamino)pyrido[2,3-d]pyrimidin-7(8H)-one

Solubility

DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL

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Our Products Cannot Be Used As Medicines Directly For Personal Use.

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