peptidyl-dipeptidase A

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Cat No.

EXWM-4053

Description

A Cl--dependent, zinc glycoprotein that is generally membrane-bound. A potent inhibitor is captopril. Important in elevation of blood pressure, through formation of angiotensin II (vasoconstrictor) and destruction of bradykinin (vasodilator). Two molecular forms exist in mammalian tissues, a widely-distributed somatic form of 150- to 180-kDa that contains two non-identical catalytic sites, and a testicular form of 90- to 100-kDa that contains only a single catalytic site. Type example of peptidase family M2

Form

Liquid or lyophilized powder

Enzyme Commission Number

EC 3.4.15.1

CAS_No

9015-82-1

Storage

Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.

Synonyms

dipeptidyl carboxypeptidase I; peptidase P; dipeptide hydrolase (ambiguous); peptidyl dipeptidase; angiotensin converting enzyme; kininase II; angiotensin I-converting enzyme; carboxycathepsin; dipeptidyl carboxypeptidase; peptidyl dipeptidase I; peptidyl-dipeptide hydrolase; peptidyldipeptide hydrolase; endothelial cell peptidyl dipeptidase; ACE; peptidyl dipeptidase-4; PDH; peptidyl dipeptide hydrolase; DCP

Reaction

Release of a C-terminal dipeptide, oligopeptide┼Xaa-Yaa, when Xaa is not Pro, and Yaa is neither Asp nor Glu. Thus, conversion of angiotensin I to angiotensin II, with increase in vasoconstrictor activity, but no action on angiotensin II

Notes

This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.

"Angiotensin Converting Enzyme" Total Products Page

Enzymes

Catalog	Product Name	EC No.	CAS No.	Source	Price
NATE-0014	Native Porcine Angiotensin Converting Enzyme	EC 3.4.15.1	9015-82-1	Porcine kidney	Inquiry
NATE-0015	Native Rabbit Angiotensin Converting Enzyme	EC 3.4.15.1	9015-82-1	Rabbit lung	Inquiry
NATE-0866	Native Bovine Angiotensin Converting Enzyme	EC 3.4.15.1		Bovine lung	Inquiry
NATE-0897	Native Rat Angiotensin Converting Enzyme	EC 3.4.15.1	9015-82-1	Rat lung	Inquiry

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Our Products Cannot Be Used As Medicines Directly For Personal Use.

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