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Project Description

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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PF-04929113 (SNX-5422)

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Cat No.

CEI-0339

CAS No.

908115-27-5

Molecular Weight

521.53

Purity

>99%

Storage

2 years at -20 centigrade

Targets

HSP90

Molecular Formula

C25H30F3N5O4

Solubility

In vitro

As a selective HSP90 inhibitor, PF-04929113 (SNX-5422) can potently inhibit HSP90 with Kd of 41 nM. PF-04929113 (SNX-5422) also shows inhibition to Her-2 degradation with IC50 of 37 nM.PF-04929113 can inhibit cell lines MCF-7, SW620, K562, SK-MEL-5, and SK-MEL-5 with IC50 of 16 nM, 19 nM, 23 nM, 25 nM, and 51 nM.