Phenylbutazone

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Cat No.

COEC-069

Description

Phenylbutazone is a compound of research interest as an anti-inflammatory and anti-proliferative agent. Several studies have investigated Phenylbutazone as an anti-inflammatory agent and its role in mediating prostaglandin synthesis. Phenylbutazone may be of interest regarding research into anti-proliferative effects as well, especially in colorectal cancer studies. In studies with human colon cancer cell lines investigating anti-proliferative capabilities of NSAIDs, Phenylbutazone was noted to have intermediate anti-proliferative potency as compared to other NSAIDs. Phenylbutazone is an inhibitor of Cox (cyclooxygenase) that is also a substrate for peroxidation by Cox.

Applications

An inhibitor of Cox

Form

Solid

CAS_No

50-33-9

Molecular Weight

308.38

Purity

≥99%

Molecular Formula

C19H20N2O2

Melting Point

106-108° C (lit.)

Solubility

Soluble in water (1 mg/ml at 25° C), ethanol (62 mg/ml at 25° C), methanol, DMSO (62 mg/ml at 25° C), and DMF (25 mg/ml).

Boiling Point

~424.9° C at 760 mmHg (Predicted)

Refractive Index

1.86 (Predicted)

Density

2.02 g/cm3 (Predicted) (tautomer)

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Our Products Cannot Be Used As Medicines Directly For Personal Use.

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