phosphohistidine phosphatase

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Cat No.

EXWM-4751

Description

This eukaryotic enzyme dephosphorylates phosphorylated histidine residues within proteins and peptides. The enzyme acts on phosphate groups attached to both the pros- and tele-nitrogen atoms, but the pros- position is somewhat preferred (by a factor of two at the most). The substrate specificity depends on the amino acid sequence or structural context of the phosphohistidine in a phosphoprotein. The enzyme is also active on free phosphoramidate and peptide-bound phospholysine.

Form

Liquid or lyophilized powder

Enzyme Commission Number

EC 3.9.1.3

Storage

Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.

Synonyms

PHPT1 (gene name); protein histidine phosphatase; PHP

Reaction

a [protein]-N-phospho-L-histidine + H2O = a [protein]-L-histidine + phosphate

Notes

This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.

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Our Products Cannot Be Used As Medicines Directly For Personal Use.

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