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Enzymes for Research, Diagnostic and Industrial Use

PIK-294

Cat No.
CEI-0104
Description
PIK-294
CAS_No
900185-02-6
Molecular Weight
489.53
Purity
>99%
Storage
2 years at -20 centigrade
Targets
p110-beta
Molecular Formula
C28H23N7O2
Solubility
No
In vitro
PIK-294 can inhibit p110-beta, p110-gamma and p110-delta with IC50 of 490 nM, 160 nM and 10 nM. PIK-294 was designed based on the inhibitor PI-103, a potent PI3K inhibitor. PIK-294 projects a m-phenol into ATP binding site. PIK-294 is 20- to 60-fold more potent than the parent compound, PIK-293. PIK-294 is one of the most potent p110delta-selective inhibitors that has been reported.

For research and industrial use only, not for personal medicinal use.

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For research and industrial use only, not for personal medicinal use.

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