Puromycin Dihydrochloride

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Cat No.

CEI-0634

Description

A nucleoside antibiotic. It inhibits protein synthesis by disrupting peptide transfer on ribosomes causing premature chain termination during translation. It is a potent translational inhibitor in both prokaryotic and eukaryotic cells. Resistance to puromycin is conferred by the puromycin N-acetyl-transferase gene (pac) from Streptomyces. Puromycin has a fast mode of action, causing rapid cell death at low antibiotic concentrations. Adherent mammalian cells are sensitive to concentrations of 2 to 5 µg /ml, while cells in suspension are sensitive to concentrations as low as 0.5 to 2 µg /ml

Appearance

Liquid

Product Overview

A protein synthesis inhibitor

CAS_No

58-58-2

Molecular Weight

156.22

Purity

>98%

Storage

-80 centigrade

Targets

Protein Synthesis

Molecular Formula

C₂₂H₂₉N₇O₅ · 2HCl

Chemical Name

3′-[α-Amino-p-methoxyhydrocinnamamido]-3′-deoxy-N,N-dimethyladenosine dihydrochloride

Shipping Conditions

Dry Ice

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Project Description:

For research and industrial use only, not for personal medicinal use.

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