PX 12

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Cat No.

CEI-0677

Description

PX-12 is an irreversible inhibitor of thioredoxin-1 (TRX-1) (Ki = 31 µM). It decreases the expression of HIF-1α ;, VEGF and iNOS (IC50 values are 7.2, ~10 and 18.1 μM respectively). Also known to display antitumor activity and inhibits tubulin polymerization in vitro.

Alias

IV-2

Appearance

White solid

Product Overview

An irreversible inhibitor of thioredoxin-1 (TRX-1)

CAS_No

141400-58-0

Molecular Weight

213.23

Purity

>95% by HPLC

Storage

-20 centigrade

Synonyms

IV-2

Targets

TXN1

Molecular Formula

C 7 H 12 N 2 S 2

Chemical Name

2-[(1-Methylpropyl)dithio]-1H-imidazole

Solubility

DMSO (20 mg/ml) or water (5 mg/ml)

Shipping Conditions

Gel pack

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Project Description:

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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