Regorafenib (methanesulfonate)

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Cat No.

CEI-1149

Description

Regorafenib (BAY 73-4506, Fluoro-Sorafenib) is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit, RET and Raf-1 with IC50 of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM, respectively.

Abbr

Regorafenib(FLT1, KDR, FLT4, PDGFRB, KIT, RET, RAF1)

Alias

FLT, FLT-1, VEGFR-1, VEGFR1

CAS_No

835621-08-4

Molecular Weight

482.82

Purity

> 95%

Stability

2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO

Storage

4 centigrade

Synonyms

FLT, FLT-1, VEGFR-1, VEGFR1

Targets

VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit, RET, Raf-1

IC50

13 nM, 4.2 nM, 46 nM, 22 nM, 7 nM, 1.5 nM, 2.5 nM,

Molecular Formula

C21H15ClF4N4O3

Chemical Name

4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide

Solubility

DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL

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Our Products Cannot Be Used As Medicines Directly For Personal Use.

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