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SB 239063
Cat No.
CEI-1519
Product Overview
SB 239063 is a potent and selective p38 MAP kinase inhibitor (IC50 = 44 nM for p38α). SB 239063 displays >220-fold selectivity over ERK, JNK1 and other kinases; ~ 3-fold more selective than SB 203580.SB 239063 reduces inflammatory cytokine production and is neuroprotective following oral administration in vivo.
CAS No.
193551-21-2
Molecular Weight
368.41
Purity
0.9937
Storage
Store at -20°C
Synonyms
SB-239063; SB239063
Targets
P38 MAP kinase
Molecular Formula
C20H21FN4O2
Chemical Name
4-[4-(4-fluorophenyl)-5-(2-methoxypyrimidin-4-yl)imidazol-1-yl]cyclohexan-1-ol
Solubility
Limited solubility
Shipping Conditions
Evaluation sample solution: ship with blue ice. All other available size: ship with RT, or blue ice upon request
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