SB 939

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Cat No.

CEI-0507

Description

An orally available pan-histone deacetylase (HDAC) inhibitor binding all HDAC isozymes with similar affinity (Kis = 16-28 nM) with the exception of HDAC6 and 7 (Kis = 247 and 104 nM, respectively). SB 939 demonstrates good bioavailability in vivo and significantly inhibits tumor growth in various xenograft mouse models at doses ranging from 25-100 mg/kg.

Alias

Pracinostat

Appearance

Pale yellow solid

Product Overview

A pan-HDAC inhibitor

CAS_No

929016-96-6

Molecular Weight

376.86

Purity

>98% by HPLC

Storage

-20 centigrade

Synonyms

Pracinostat

Targets

HDAC

Molecular Formula

C20H30N4O2

Chemical Name

3-[2-butyl-1-[2-(diethylamino)ethyl]-1H-benzimidazol-5-yl]-N-hydroxy-2E-propenamide

Solubility

DMSO (~ 50 mM)

Shipping Conditions

Gel pack

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Project Description:

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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