SCD1 Inhibitor

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Cat No.

CEI-0644

Description

Cell-permeable. A potent and selective inhibitor of SCD1(stearoyl-CoA desaturase 1) (In vitro: IC₅₀ = 37 nM for hSCD1, <4 nM for mSCD1). Also exhibited in vivo efficacy with dose-dependent desaturation index lowering effect. SCD1 inhibition resulted in alterations in macrophage membrane lipid composition and marked hypersensitivity to toll-like receptor 4 agonists.

Alias

A939572

Appearance

Lyophilized solid

Product Overview

A SCD1(stearoyl-CoA desaturase 1) inhibitor

Molecular Weight

695.7

Purity

Single spot by TLC

Storage

-20 centigrade

Synonyms

A939572

Targets

SCD

Molecular Formula

C₂₀H₂₂ClN₃O₃

Chemical Name

4-(2-Chlorophenoxy)-N-(3-(3-methylcarbamoyl)phenyl)piperidine-1-carboxamide

Solubility

DMSO (20 mM)

Shipping Conditions

Gel pack

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Project Description:

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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