single-stranded DNA cytosine deaminase

inquiry

Cat No.

EXWM-4566

Description

The enzyme exclusively catalyses deamination of cytosine in single-stranded DNA. It preferentially deaminates five-nucleotide bubbles. The optimal target consists of a single-stranded NWRCN motif (W = A or T, R = A or G). The enzyme initiates antibody diversification processes by deaminating immunoglobulin sequences.

Form

Liquid or lyophilized powder

Enzyme Commission Number

EC 3.5.4.38

Storage

Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.

Synonyms

AID; activation-induced deaminase; AICDA (gene name); activation-induced cytidine deaminase

Reaction

cytosine in single-stranded DNA + H2O = uracil in single-stranded DNA + NH3

Notes

This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.

Name:

Email *

Phone:*

Company/Institution:

Country or Region:

Quantity:

Services & Products Interested *

Project Description:

Our Products Cannot Be Used As Medicines Directly For Personal Use.

Products

Online Inquiry