single-stranded DNA cytosine deaminase

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Cat No.

EXWM-4566

Description

The enzyme exclusively catalyses deamination of cytosine in single-stranded DNA. It preferentially deaminates five-nucleotide bubbles. The optimal target consists of a single-stranded NWRCN motif (W = A or T, R = A or G). The enzyme initiates antibody diversification processes by deaminating immunoglobulin sequences.

Form

Liquid or lyophilized powder

Enzyme Commission Number

EC 3.5.4.38

Storage

Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.

Synonyms

AID; activation-induced deaminase; AICDA (gene name); activation-induced cytidine deaminase

Reaction

cytosine in single-stranded DNA + H2O = uracil in single-stranded DNA + NH3

Notes

This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.

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Project Description:

For research and industrial use only, not for personal medicinal use.

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