Smad3 Inhibitor, SIS3

inquiry

Cat No.

CEI-0657

Description

A potent and selective inhibitor of Smad3 function. SIS3 selectively inhibits TGF-β1/ALK5-induced Smad3 phosphorylation. Also inhibits the TGF-β1 effect on type I procollagen expression at the transcriptional levels via the Smad3-binding site.

Appearance

Pale yellow solid

Product Overview

A Smad3 inhibitor

CAS_No

521984-48-5

Molecular Weight

406.44

Purity

>90% by NMR

Storage

-20 centigrade

Targets

SMAD3

Molecular Formula

C 28 H 27 N 3 O 3 . HCl

Chemical Name

(2E)-1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-propenone hydrochloride

Solubility

DMSO

Shipping Conditions

Gel pack

First Name:

Last Name:

Email *

Phone Number:

Company/Institution:

Country or Region:

Quantity:

Services & Products of Interested

Project Description:

For research and industrial use only, not for personal medicinal use.

Products

Online Inquiry