Sp-Adenosine 3',5'-cyclic monophosphorothioate triethylammonium salt

Cat No.

COEC-116

Description

Sp-Diastereomer of adenosine 3',5'-cyclic monophosphorothioate is a potent, membrane-permeable activator of PKA (cAMP dependent protein kinase I and II). Mimics the effects of cAMP as a second messenger in numerous systems while being resistant to cyclic nucleotide phosphodiesterases. Exhibits greater specificity and affinity than forskolin and cAMP analogs such as dibutyryl-cAMP. Sp-Adenosine 3',5'-cyclic monophosphorothioate triethylammonium salt hydrate is an activator of Epac.

Applications

A membrane permeable activator of cAMP dependent protein kinase I and II

Form

Solid

CAS No.

93602-66-5

Molecular Weight

446.46

Purity

≥98%

Synonyms

Sp-Cyclic 3',5'-hydrogen phosphorothioate adenosine; Sp-cAMPS triethylammonium salt

Molecular Formula

C10H11N5O5PS•C6H16N

Melting Point

212-213° C

Solubility

Soluble in water.

Refractive Index

1.59 (Predicted)

Density

1.44 g/cm3 (Predicted)

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