Sphingosine Kinase Inhibitor, SKI-II

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Cat No.

CEI-0666

Description

Cell-permeable. SKI-II is selective a non-lipid sphingosine kinase (SK) inhibitor. It displays non-ATP-competitive inhibition of human recombinant GST-SK 1 with an IC50 value of 0.5 µM, with no inhibition against ERK2, PI3-kinase, or PKCα ; at concentrations up to 60 µM.

Appearance

Pale yellow solid

Product Overview

A non-lipid pan-sphingosine kinase (SK) inhibitor

CAS_No

312636-16-1

Molecular Weight

697.99

Purity

>80% by HPLC

Storage

-20 centigrade

Targets

SPHK1

Molecular Formula

C 15 H 11 CIN 2 OS

Chemical Name

4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol

Solubility

DMSO or EtOH

Shipping Conditions

Gel pack

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Project Description:

For research and industrial use only, not for personal medicinal use.

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