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Cat No.

CEI-0498

Description

Potent inhibitor of yeast NAD⁺dependent histone deacetylase Sir2p (IC50 = 60 µM). Sensitizes mammalian cells to a variety of DNA-damaging agents by abrogating Sir2p activity on p53. Acts by either altering or blocking access to the acetylated histone binding pocket.

Appearance

Lyophilized solid

Product Overview

A HDAC inhibitor

CAS_No

5690-03-9

Molecular Weight

513.49

Purity

>95% by HPLC

Storage

-20 centigrade

Targets

HDAC

Molecular Formula

C₁₃H₁₀O₂

Chemical Name

1,2-Dihydro-3H-naphtho[2,1-b]pyran-3-one

Solubility

DMSO (200 mg/ml)

Shipping Conditions

Gel pack

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Project Description:

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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