taxadiene 5α-hydroxylase

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Cat No.

EXWM-1048

Description

This microsomal cytochrome-P-450-dependent enzyme is involved in the biosynthesis of the diterpenoid antineoplastic drug Taxol (paclitaxel). The reaction includes rearrangement of the 4(5)-double bond to a 4(20)-double bond, possibly through allylic oxidation.

Form

Liquid or lyophilized powder

Enzyme Commission Number

EC 1.14.99.37

CAS_No

9035-51-2

Storage

Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.

Reaction

taxa-4,11-diene + AH2 + O2 = taxa-4(20),11-dien-5α-ol + A + H2O

Notes

This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.

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Our Products Cannot Be Used As Medicines Directly For Personal Use.

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