TC-DAPK 6

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Cat No.

CEI-1551

Product Overview

Death-associated protein kinase (DAPK) is a serine/threonine protein kinase implicated in diverse programmed cell death pathways. DAPK is a promising target protein for the treatment of ischemic diseases. TC-DAPK 6 is an oxazalone compound that acts as a potent, ATP-competitive, and highly selective death-associated protein kinase (DAPK) inhibitor (IC50 = 69 and 225 nM against DAPK1 and DAPK3, respectively, with 10 μM ATP); while exhibiting much reduced or no activity against a panel of 48 other kinases even at concentrations as high as 10 μM.

CAS_No

315694-89-4

Molecular Weight

276.29

Purity

0.98

Storage

Store at -20°C

Synonyms

DAPK inhibitor

Targets

DAPK

Molecular Formula

C17H12N2O2

Chemical Name

(4E)-2-[(E)-2-phenylethenyl]-4-(pyridin-3-ylmethylidene)-1,3-oxazol-5-one

Solubility

Soluble in DMSO > 10 mM

Shipping Conditions

Evaluation sample solution: ship with blue ice. All other available size: ship with RT, or blue ice upon request

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Project Description:

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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