Telatinib (BAY 57-9352)

inquiry

Cat No.

CEI-0023

CAS_No

332012-40-5

Molecular Weight

409.83

Purity

>99%

Storage

2 years at -20 centigrade

Targets

VEGFR2

Molecular Formula

C20H16ClN5O3

Solubility

In vitro

Telatinib (BAY 57-9352), a small molecule angiogenesis inhibitor, can potently inhibit VEGFR2, VEGFR3, c-Kit and PDGFRbeta with IC50 of 6 nM, 4 nM, 1 nM and 15 nM. Telatinib (BAY 57-9352) impairs vascular function, induces rarefaction, and causes hypertension. Telatinib can inhibit the autophosphorylation of VEGFR2 autophosphorylation with an IC50 of 19 nM, and telatinib also suppresses VEGF-dependent proliferation of human umbilical vein endothelial cells with an IC50 of 26 nM.

Name:

Email *

Phone:*

Company/Institution:

Country or Region:

Quantity:

Services & Products Interested *

Project Description:

Our Products Cannot Be Used As Medicines Directly For Personal Use.

Products

Online Inquiry