tert-Butyl N4-trityl-L-asparaginyl-L-leucinate

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Cat No.

CEGZ-6919

Description

tert-Butyl N4-trityl-L-asparaginyl-L-leucinate is a protected dipeptide ester comprising asparagine, protected at the side-chain carboxamide with a trityl group, linked to a C-terminal leucine tert-butyl ester. The free N-terminal amino group allows direct use in chain elongation.

Applications

Used as a building block in solid-phase and solution-phase peptide synthesis for the preparation of asparagine-leucine-containing peptides and peptide intermediates.

Product Overview

The trityl protection on asparagine suppresses side reactions associated with the carboxamide group during coupling, while the tert-butyl ester protects the C-terminus and is removed under acidic conditions. Such preformed dipeptides simplify the assembly of Asn-Leu-containing sequences.

CAS_No

1431625-52-3

Molecular Weight

543.7

Storage

Store in a tightly closed container in a cool, dry place.

Synonyms

H-Asn(Trt)-Leu-OtBu; N4-trityl-L-asparaginyl-L-leucine tert-butyl ester

Molecular Formula

C33H41N3O4

Notes

For research and development use only.

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Project Description:

For research and industrial use only. Not intended for personal medicinal use. Certain food-grade products are suitable for formulation development in food and related applications.

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