tissue kallikrein

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Cat No.

EXWM-4129

Description

Formed from tissue prokallikrein by activation with trypsin. In peptidase family S1 (trypsin family). A large number of tissue kallikrein-related sequences have been reported for rats and mice, though fewer seem to exist in other mammals. The few that have been isolated and tested on substrates include mouse γ-renin (EC 3.4.21.54), submandibular proteinase A, epidermal growth-factor-binding protein, nerve growth factor γ-subunit, rat tonin, submaxillary proteinases A and B, T-kininogenase, kallikreins k7 and k8 and human prostate-specific antigen (γ-seminoprotein,)

Form

Liquid or lyophilized powder

Enzyme Commission Number

EC 3.4.21.35

CAS_No

389069-73-2

Storage

Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.

Synonyms

glandular kallikrein; pancreatic kallikrein; submandibular kallikrein; submaxillary kallikrein; kidney kallikrein; urinary kallikrein; kallikrein; salivary kallikrein; kininogenin; kininogenase; callicrein; glumorin; padreatin; padutin; kallidinogenase; bradykininogenase; depot-padutin; urokallikrein; dilminal D; onokrein P

Reaction

Preferential cleavage of Arg┼ bonds in small molecule substrates. Highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met┼ or Leu┼. The rat enzyme is unusual in liberating bradykinin directly from autologous kininogens by cleavage at two Arg┼ bonds

Notes

This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.

"Kallikrein" Total Products Page

Enzymes

Catalog	Product Name	EC No.	CAS No.	Source	Price
NATE-0143	Native Clostridium histolyticum Clostripain	EC 3.4.22.8	9028-00-6	Clostridium histolyticum	Inquiry
NATE-0218	Native Mouse Endoproteinase Arg-C	EC 3.4.21.35	82047-85-6	Mouse submaxillary gland	Inquiry
NATE-0361	Native Human Kallikrein	EC 3.4.21.34	9001-01-8	Human plasma	Inquiry
NATE-0362	Native Porcine Kallikrein	EC 3.4.21.35	9001-01-8	Porcine pancreas	Inquiry

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Our Products Cannot Be Used As Medicines Directly For Personal Use.

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