tRNA (cytosine34-C5)-methyltransferase

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Cat No.

EXWM-1804

Description

The human enzyme is specific for C5-methylation of cytosine34 in tRNA precursors. The intron in the human pre-tRNALeu(CAA) is indispensable for the C5-methylation of cytosine in the first position of the anticodon. It is not able to form 5-methylcytosine at positions 48 and 49 of human and yeast tRNA precursors.

Form

Liquid or lyophilized powder

Enzyme Commission Number

EC 2.1.1.203

Storage

Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.

Synonyms

hTrm4 Mtase; hTrm4 methyltransferase; hTrm4 (gene name); tRNA:m5C-methyltransferase (ambiguous)

Reaction

S-adenosyl-L-methionine + cytosine34 in tRNA precursor = S-adenosyl-L-homocysteine + 5-methylcytosine34 in tRNA precursor

Notes

This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.

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Project Description:

For research and industrial use only, not for personal medicinal use.

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