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U0126
Cat No.
CEI-1023
Description
U0126 is a selective inhibitor of mitogen-activated protein kinase kinases, MEK-1 and MEK-2. It is a weak inhibitor of PKC, Raf, ERK, JNK, MEKK, MKK-3, MKK-4/SEK, MKK-6, Abl, Cdk2 and Cdk4.
Abbr
U0126(MAP2K1, MAP2K2)
Alias
CFC3, MAPKK1, MEK1, MKK1, PRKMK1
Appearance
White to off-white crystalline solid; granular or powder.
CAS No.
109511-58-2
Molecular Weight
380.49
Purity
>99%
Storage
Store at or below -20 centigrade.
Synonyms
CFC3, MAPKK1, MEK1, MKK1, PRKMK1
Targets
MEK-1, MEK-2
IC50
0.07 μM, 0.06 μM
Molecular Formula
C18H16N6S2
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