USP7/USP47 Inhibitor, P 22077

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Cat No.

CEI-0696

Description

A cell-permeable inhibitor of the ubiquitin-specific protease (IC50 = 8.6 µM) and the closely related deubiquitinase (DUB) USP47. P22077 displays weak or no inhibition (EC₅₀ >50 µM) towards a panel of 14 isopeptidases and other proteases. Inhibits USP7-mediated p53 deubiquitination.

Alias

DUB inhibitor

Appearance

White to off-white solid

Product Overview

A USP7/USP47 inhibitor

CAS_No

1247819-59-5

Molecular Weight

264.3

Purity

>99%

Storage

-20 centigrade

Synonyms

DUB inhibitor

Targets

USP7, USP47

Molecular Formula

C 12 H 7 F 2 NO 3 S

Chemical Name

1-(5-(2,4-Difluorophenylthio)-4-nitrothiophen-2-yl)ethanone

Solubility

DMSO (60 mg/ml) of EtOH (2 mg/ml)

Shipping Conditions

Gel Pack

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Project Description:

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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