Valsartan (Diovan)

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Cat No.

CEI-0369

Description

Valsartan (Diovan) is an angiotensin II receptor antagonist with IC50 of ranging from 39.5 to 116 uM.

CAS_No

137862-53-4

Molecular Weight

435.52

Purity

>98%

Storage

2 years -20centigrade Powder

Targets

angiotensin II receptor

Molecular Formula

C24H29N5O3

Chemical Name

(2S)-3-methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl] methyl]amino]butanoic acid

Solubility

DMSO 87 mg/mL,Water

In vitro

valsartan is a potent, highly selective, and orally active antagonist at the angiotensin II (AII) AT1-receptor. Valsartan compets with [125I]-AII at its specific binding sites in rat aortic smooth muscle cell membranes (AT1-receptor subtype) with a Ki of 2.38 nM, but is about 30,000 times less active in human myometrial membranes (AT2-receptor subtype).

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Our Products Cannot Be Used As Medicines Directly For Personal Use.

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