Vinblastine Sulfate

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Cat No.

CEI-0563

Description

A plant alkaloid that arrests the cell cycle in G2/M phase by blocking mitotic spindle formation. Inhibits normal microtubule assembly and causes aberrant tubulin polymerization. Blocks binding of tubulin to microtubule proteins. Induces apoptosis. Triggers Raf-1 activation, phosphorylation of Bcl-2 family proteins and induction of p53 expression. Cancer chemotherapeutic agent.

Alias

Vincaleukoblastine sulfate salt; VLB

Appearance

White solid

Product Overview

A tubulin polymerrization inhibitor

CAS_No

143-67-9

Molecular Weight

271.27

Purity

>98% by HPLC

Storage

Synonyms

Vincaleukoblastine sulfate salt; VLB

Targets

MGMT

Molecular Formula

C₄₆H₅₈N₄O₉S.H₂SO₄

Solubility

DMSO (100 mM)

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Our Products Cannot Be Used As Medicines Directly For Personal Use.

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