Z-DEVD-FMK

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Cat No.

CEI-0432

Description

A synthetic peptide that irreversibly inhibits activity of DEVD-dependent caspases (e.g., caspase-3 and caspase-7) and blocks apoptosis. The inhibitor is designed as a methyl ester to facilitate cell permeability. The product can be used for both in vitro and in vivo studies. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).

Alias

Z-DEVD-FMK, Caspase-3 inhibitor (fluoromethylketone)

Appearance

Crystalline solid

Product Overview

A caspase-3 inhibitor

CAS_No

210344-95-9

Molecular Weight

462.56

Purity

>98% by HPLC

Storage

-20 centigrade

Synonyms

Z-DEVD-FMK, Caspase-3 inhibitor (fluoromethylketone)

Targets

caspase-3

Molecular Formula

C₃₀H₄₁FN₄O₁₂

Solubility

DMSO (~25 mg/ml) or Ethanol (~ 15 mg/ml)

Shipping Conditions

Gel pack

Amino Acid Sequence

Z-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-FMK

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Project Description:

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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