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Calpain 1

Official Full Name
Calpain 1
Background
Caplain 1 is a neutral calcium-dependent cysteine protease containing the EF-hand motif. The protease consists of two subunits; the larger subunit has four domains that are homologous with papain and calmodulin. The smaller subunit has one domain that shares homology with calmodulin. It is activated by micromolar levels of calcium and hence, it is also called as micro-calpain. Its activation leads to cellular protein degradation, neuronal cell degeneRation, and autoimmune demyelinating diseases such as multiple sclerosis.
Synonyms
calpain 1, μ-calpain; calcium-activated neutral protease I; EC 3.4.22.52

Catalog
ProductName
EC No.
CAS No.
Source
Price
CatalogEXWM-4227
ProductNamecalpain-1
EC No.EC 3.4.22.52
CAS No.78990-62-2
Source
CatalogNATE-1625
EC No.
CAS No.
SourcePorcine Erythro...
CatalogNATE-0100
EC No.EC 3.4.22.52
CAS No.78990-62-2
SourceHuman

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