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FAK

Official Full Name
FAK
Background
FAK is a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. At least four transcript variants encoding four different isoforms have been found for this gene, but the full-length natures of only two of them have been determined.
Synonyms
Focal adhesion kinase 1; EC 2.7.10.2; FADK 1; pp125FAK; Protein-tyrosine kinase 2; FAK; FADK; FAK1; PTK2; FRNK; PPP1R71; p125FAK

Catalog
ProductName
EC No.
CAS No.
Source
Price
CatalogEXWM-3127
EC No.EC 2.7.10.2
CAS No.
Source
CatalogNATE-0800
EC No.EC 2.7.10.2
CAS No.
SourceBaculovirus, SF...

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