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PTPase

Official Full Name
PTPase
Background
Protein tyrosine phosphatases are a group of enzymes that remove phosphate groups from phosphorylated tyrosine residues on proteins. Protein tyrosine (pTyr) phosphorylation is a common post-translational modification that can create novel recognition motifs for protein interactions and cellular localization, affect protein stability, and regulate enzyme activity. As a consequence, maintaining an appropriate level of protein tyrosine phosphorylation is essential for many cellular functions. Tyrosine-specific protein phosphatases (PTPase; EC 3.1.3.48) catalyse the removal of a phosphate group attached to a tyrosine residue, using a cysteinyl-phosphate enzyme intermediate. These enzymes are key regulatory components in signal transduction pathways (such as the MAP kinase pathway) and cell cycle control, and are important in the control of cell growth, proliferation, differentiation, transformation, and synaptic strengthening.
Synonyms
YOP Protein Tyrosine Phosphatase; Protein tyrosine phosphatase; Tyrosine-specific protein phosphatases; PTPase

Catalog
ProductName
EC No.
CAS No.
Source
Price
CatalogNATE-0642
EC No.
CAS No.
SourceE. coli
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