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Kininogen


Official Full Name
Kininogen
Background
High Molecular Weight Kininogen (HK) is a non-enzymatic cofactor of the contact activation system. HK is thought to have two functions in the contact activation system. First, HK links Prekallikrein to a negatively charged surface thereby allowing activation of Kallikrein by surface bound Factor a-XIIa. HK also forms a complex with Factor XI and accelerates its activation to XIa by a-XIIa. Additionally HK serves as a source of Bradykinin, a potent vasoactive peptide important in hypotension studies. The protein purity is determined by SDS-PAGE.
Synonyms
Human Kininogen (Single Chain High Molecular Weight); Kininogen

Catalog
Product Name
EC No.
CAS No.
Source
Price
CatalogCZY-029
EC No.
CAS No.
SourceHuman
CatalogCZY-028
EC No.
CAS No.
SourceHuman

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