Sphingolipids are a group of lipids which contain a series of aliphatic amino alcohols as the backbone, including sphingosine. Sphingolipids have wide distributions ranging from yeasts to mammals. In signal transmission and cell recognition, sphingolipids have indispensable roles. Once sphingolipids metabolism becomes disordered, it will arouse huge impacts on neural tissues. The simplest sphingolipids are ceramides, which have been found useful in topic medicines and cosmetic products. Glycolipids are a large group of sphingolipids which contain sugar molecules in their structures.