Description
β--lactamase inactivates β-lactam antibiotics by breaking open the β-lactam ring.
Abbr
β-Lactamase, Recombinant
Form
Lyophilized powder containing sodium chloride, potassium phosphate and sorbitol.
Enzyme Commission Number
EC 3.5.2.6
Activity
600-1500 IU beta-lactamase I per vial; 60-100 IU beta-lactamase II per vial
Unit Definition
One unit will hydrolyze 1.0 μmole substrate per min (βI: benzylpenicillin; βII: cephalosporin C) in phosphate buffer, pH 7.0 at 25°C.
Synonyms
β-lactamase; penicillinase; cephalosporinase; neutrapen; penicillin β-lactamase; exopenicillinase; ampicillinase; penicillin amido-β-lactamhydrolase; penicillinase I, II; β-lactamase I-III; β-lactamase A, B, C; β-lactamase AME I; cephalosporin-β-lactamase; EC 3.5.2.6; 9073-60-3
