5-Lipoxygenase from human, Recombinant

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Cat No.

NATE-1249

Description

Arachidonate 5-lipoxygenase, also known as ALOX5, 5-lipoxygenase, 5-LOX, or 5-LO, is an enzyme that in humans is encoded by the ALOX5 gene. Arachidonate 5-lipoxygenase is a member of the lipoxygenase family of enzymes. It transforms EFAs into leukotrienes and is a current target for pharmaceutical intervention in a number of diseases.

Abbr

5-LOX, Recombinant (Human)

Alias

5-LOX

Source

S9 insect cells

Species

Human

Form

A solution in 100 mM Tris-HCl, pH 8.0, containing 5 mM EGTA, 1mM CaCl2, and 30% glycerol

Enzyme Commission Number

EC 1.13.11.34

Activity

1,259.96 U/ml

CAS_No

80619-02-9

Molecular Weight

78 kDa

Unit Definition

One unit of enzyme consumes one nmol of oxygen per minute at 25°C in 50 mM Tris-HCl buffer, pH 7.5, containing 100 µM arachidonate, 2 mM CaCl2, 1 mM ATP.

Stability

As supplied, 6 months from the QC date provided on the Certificate of Analysis, when stored properly

Storage

at -80°C

Synonyms

Arachidonate 5-lipoxygenase; ALOX5; 5-lipoxygenase; 5-LOX; 5-LO; 5LPG; LOG5

"Lipoxygenase" Total Products Page

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Catalog	Product Name	EC No.	CAS No.	Source	Price
NATE-0407	Native Glycine max (soybean) Lipoxidase	EC 1.13.11.12	9029-60-1	Glycine max (soybean)	Inquiry
NATE-1248	15-Lipoxygenase-2 from human, Recombinant	EC 1.13.11.33		E. coli	Inquiry
EXWM-0532	linoleate 13S-lipoxygenase	EC 1.13.11.12	9029-60-1		Inquiry
EXWM-0552	arachidonate 15-lipoxygenase	EC 1.13.11.33	82249-77-2		Inquiry

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Our Products Cannot Be Used As Medicines Directly For Personal Use.

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