Description
Pyroglutamate aminopetidase is an enzyme that digests proteins.
Abbr
Pyrase, Native (Bacillus sp.)
Applications
Pyroglutamate aminopetidase is used to digest proteins for subsequent analysis, such as amino acid sequencing. Pyroglutamate aminopeptidase is used to hydrolyze and activate various prodrugs.
Enzyme Commission Number
EC 3.4.19.3
Activity
> 0.11 units/mg protein
Unit Definition
1 U corresponds to the amount of enzyme which hydrolyzes 1 μmol Pyroglutamate-p-nitroanilide per minute at pH 7.0 and 37°C
Warnings
Enzyme for cleavage of N-terminal pyroglutamate from peptides prior to Edman sequencing
Synonyms
pyroglutamyl-peptidase I; Pyroglutamate aminopeptidase; EC 3.4.19.3; 5-oxoprolyl-peptidase; pyrase; pyroglutamate aminopeptidase; pyroglutamyl aminopeptidase; L-pyroglutamyl peptide hydrolase; pyrrolidone-carboxyl peptidase; pyrrolidone-carboxylate peptidase; pyrrolidonyl peptidase; L-pyrrolidonecarboxylate peptidase; pyroglutamidase; pyrrolidonecarboxylyl peptidase; 9075-21-2
