Products

Enzymes for Research, Diagnostic and Industrial Use

Native Human β-N-Acetylglucosaminidase


Cat No.
NATE-0781
Description
This enzyme, sometimes called β-N-acetylhexosaminidase, is reported to liberate terminal β-linked N-acetylglucosamine and N-acetylgalactosamine from a variety of substrates. The activity of β-N-actylglucosaminidase may be determined with the chromogenic substrate p-nitrophenyl-N-acetyl-β-D-glucosaminide. β-N-actylglucosaminidase hydrolyzes the terminal nonreducing N-acetyl-D-hexosamine residues. This enzyme contains two predominant isozymes, Hex A, a heterodimer, and Hex B, a homodimer. N-acetylglucosamine, acetamide, N-2-acetamido-2-deoyglucosylamine, N-acetylnojirimycin, and N-acetyldeoxynojirmycin are known inhibitors.
Abbr
β-N-Acetylglucosaminidase, Native (Human)
Source
Human placenta
Species
Human
Applications
β-N-acetylglucosaminidase is a lysosomal enzyme used to hydrolyze N-acetyl-β-D-glucosaminides and N-acetyl-β-Dgalactosaminides. It is used in chemoenzymatic synthesis of oligosaccharides based on their effective transglycosylation of β-GlcNAc and β-GalNAcc. It may be a useful tool to study Alzheimer’s Disease.
Form
ammonium sulfate suspension. Suspension in 2.4 M (NH4)2SO4 containing 0.15 M NaCl and 0.1 M sodium phosphate, pH 6.0
Enzyme Commission Number
EC 3.2.1.52
Activity
6-20 units/mg protein
CAS No.
9012-33-3
Unit Definition
One unit will hydrolyze 1.0 μmole of p-nitrophenyl N-acetyl-β-D-glucosaminide to p-nitrophenol and N-acetyl-D-glucosamine per min at the pH 4.25 at 25°C.
Storage
2-8°C
Pathway
Other glycan degradation, organism-specific biosystem;Other glycan degradation, conserved biosystem; Amino sugar and nucleotide sugar metabolism, organism-specific biosystem; Amino sugar and nucleotide sugar metabolism, conserved biosystem; Glycosaminoglycan degradation, organism-specific biosystem; Glycosaminoglycan degradation, conserved biosystem; Glycosphingolipid biosynthesis-ganglio series, organism-specific biosystem; Glycosphingolipid biosynthesis-ganglio series, conserved biosystem; Glycosphingolipid biosynthesis-globo series, organism-specific biosystem
Function
mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity; beta-N-acetylhexosaminidase activity; cation binding; hydrolase activity, hydrolyzing O-glycosyl compounds; protein heterodimerization activity
Synonyms
hexosaminidase; β-acetylaminodeoxyhexosidase; N-acetyl-β-D-hexosaminidase; N-acetyl-beta-hexosaminidase; β-hexosaminidase; β-acetylhexosaminidinase; β-D-N-acetylhexosaminidase; β-N-acetyl-D-hexosaminidase; β-N-acetylglucosaminidase; hexosaminidase A; N-acetylhexosaminidase; β-D-hexosaminidase; 9012-33-3; EC 3.2.1.52
Download Datasheet:
SDS:


“β-N-Acetylhexosaminidase” Total Products Page

Inquiry
Related Products
Catalog
Product Name
EC No.
CAS No.
Source
Price
CatalogNATE-0779
EC No.EC 3.2.1.52
CAS No.9012-33-3
SourceBovine kidney
CatalogNATE-0780
EC No.EC 3.2.1.52
CAS No.9012-33-3
SourceCanavalia ensiformis
CatalogNATE-0782
EC No.3.2.1.52
CAS No.9012-33-3
SourceE. coli
CatalogNATE-0783
EC No.
CAS No.
SourceJack bean
+ See More >>
Related Services
Related Protocols
b-n-acetylglucosaminidase -Enzymatic Assay Protocol
Online Inquiry
Name:
*Phone:
*E-mail Address:
Country or Region:
Company/Institution:
*Products or Services of Interest:
Quantity:
Project Description:
Our products are not intended for direct clinical use!
*Verification Code:
Verification code

Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.


Sitemap | Privacy Policy | Terms and Conditions
Copyright ©2011 - 2021 Creative Enzymes.
Contact Us address-USA
Email: info@creative-enzymes.com
Tel:
Fax: fax
Distributors To view the contact information for a specific location, select the desired country or region:
     
0
Click unfold / close
Inquiry Basket
Delete selected Check Out
Decide to move out of the shopping cart??

Sure No, Back
 

Please choose product!

< Go Back
You have already added to buy this product