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Native Rabbit Glycerol-3-phosphate dehydrogenase


Cat No.
NATE-0313
Description
Glycerol-3-phosphate dehydrogenase (GPDH) is an enzyme that catalyzes the reversible redox conversion of dihydroxyacetone phosphate (aka glycerone phosphate, outdated) to sn-glycerol 3-phosphate. Glycerol-3-phosphate dehydrogenase serves as a major link between carbohydrate metabolism and lipid metabolism. It is also a major contributor of electrons to the electron transport chain in the mitochondria.
Abbr
GPDH, Native (Rabbit)
Alias
GPDH
Source
Rabbit Muscle
Species
Rabbit
Appearance
White to off-white powder
Form
Lyophilized
Enzyme Commission Number
EC 1.1.1.8
Activity
> 15 U/mg solid
CAS No.
9075-65-4
Contaminants
LDH: 0.3%PK: 0.3%TPI: 10%Aldolase: 0.05%Glycerol Kinase: 0.01
Molecular Weight
75200
Purity
Purified
Specificity
> 100 U/mg protein
Unit Definition
One unit will catalyze the reduction of one micromole of dihydroxyacetone phosphate to alpha-glycerophosphate per minute at pH 7.4 and 25°C.
Storage
-20°C
Pathway
Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Glycerophospholipid biosynthesis, organism-specific biosystem; Glycerophospholipid metabolism, conserved biosystem
Function
NAD binding; glycerol-3-phosphate dehydrogenase [NAD+] activity; protein homodimerization activity
Synonyms
Glycerol-3-phosphate dehydrogenase; GPDH; alpha glycerol-3-phosphate dehydrogenase; alphaGPDH; glycerolphosphate dehydrogenase; EC 1.1.1.8; 9075-65-4; α-glycerol phosphate dehydrogenase (NAD); α-glycerophosphate dehydrogenase (NAD); glycerol 1-phosphate dehydrogenase; glycerol phosphate dehydrogenase (NAD); glycerophosphate dehydrogenase (NAD); hydroglycerophosphate dehydrogenase; L-α-glycerol phosphate dehydrogenase; L-α-glycerophosphate dehydrogenase; L-glycerol phosphate dehydrogenase; L-glycerophosphate dehydrogenase; NAD-α-glycerophosphate dehydrogenase; NAD-dependent glycerol phosphate dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase; NAD-L-glycerol-3-phosphate dehydrogenase; NAD-linked glycerol 3-phosphate dehydrogenase; NADH-dihydroxyacetone phosphate reductase; glycerol-3-phosphate dehydrogenase (NAD)
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