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Native Staphylococcus aureus Sphingomyelinase


Cat No.
NATE-0673
Description
Sphingomyelin phosphodiesterase is a hydrolase enzyme that is involved in sphingolipid metabolism reactions. SMase is a member of the DNase I superfamily of enzymes and is responsible for breaking sphingomyelin (SM) down into phosphocholine and ceramide. The activation of SMase has been suggested as a major route for the production of ceramide in response to cellular stresses.
Abbr
SMase, Native (Staphylococcus aureus)
Alias
SMase
Source
Staphylococcus aureus
Form
buffered aqueous glycerol solution; Solution in 50% glycerol containing 0.25 M phosphate buffer, pH 7.5
Enzyme Commission Number
EC 3.1.4.12
Activity
100-300 units/mg protein (Lowry)
CAS No.
9031-54-3
Unit Definition
One unit will hydrolyze 1.0 μmol of TNPAL-sphingomyelin per min at pH 7.4 at 37°C.
Storage
2-8°C
Synonyms
Sphingomyelin phosphodiesterase; EC 3.1.4.12; neutral sphingomyelinase; 9031-54-3; sphingomyelin cholinephosphohydrolase; sphingomyelinase; SMase
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Related Services
Related Protocols
SPHINGOMYELINASE -Enzymatic Assay Protocol
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