Carboxypeptidase-B rat, Recombinant

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Cat No.

NATE-0153

Description

Carboxypeptidase B (or peptidyl-L-lysine (-L-arginine) hydrolase) catalyzes the hydrolysis of the basic amino acids, lysine, arginine, and ornithine from the C-terminal position of polypeptides. It has been shown to be a single polypeptide of 34 kDa Da. Trypsin is capable of converting native enzyme to the active enzyme, carboxypeptidase B II in vitro. The optimum pH is found to be 9.0. The enzyme may be used for sequence analysis by successive cleavage of C-terminal basic amino acids. It can also be used as a serum marker for the diagnosis of acute pancreatitis.

Abbr

CPB1, Recombinant (Rat)

Alias

CPB1

Source

E. coli

Species

Rat

Applications

Carboxypeptidase B (EC 3.4.17.2, protaminase, pancreatic carboxypeptidase B, tissue carboxypeptidase B, peptidyl-L-lysine [L-arginine]hydrolase) is a carboxypeptidase that preferentially acts upon basic amino acids, such as arginine and lysine. This serum enzyme is also responsible for rapidly metabolizing the C5a protein into C5a des-Arg, with one less amino acid.

Product Overview

Caspase 3 is synthesized as a 32 kDa proenzyme. The active enzyme is a heterodimer of two large (17 kDa) subunits and two small (12 kDa) subunits.

Form

Lyophilized from 20 mM Tris, pH 8.0 + 50 mM NaCl.

Enzyme Commission Number

EC 3.4.17.2

Activity

50-55 units/mg protein carboxypeptidase B

CAS_No

9025-24-5

Storage

−20°C

Pathway

Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Protein digestion and absorption, organism-specific biosystem

Function

carboxypeptidase activity; metallocarboxypeptidase activity; zinc ion binding

Synonyms

carboxypeptidase B; protaminase; CPB1; pancreatic carboxypeptidase B; tissue carboxypeptidase B; peptidyl-L-lysine [L-arginine]hydrolase; EC 3.4.17.2; 9025-24-5

"CPB1" Total Products Page

Enzymes

Catalog	Product Name	EC No.	CAS No.	Source	Price
NATE-0151	Native Human Carboxypeptidase B	EC 3.4.17.2	9025-24-5	Human pancreas	Inquiry
NATE-0152	Native Porcine Carboxypeptidase B	EC 3.4.17.2	9025-24-5	Porcine pancreas	Inquiry
NATE-0993	Carboxypeptidase-B from rat, Recombinant			Pichia pastoris	Inquiry
NATE-1147	Carboxypeptidase B from Porcine, Recombinant	EC 3.4.17.2		Porcine	Inquiry

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Our Products Cannot Be Used As Medicines Directly For Personal Use.

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