Native α-1,2-Fucosidase solution

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Cat No.

NATE-0259

Description

Tissue alpha-L-fucosidase is an enzyme that in humans is encoded by the FUCA1 gene. Alpha-Fucosidase is an enzyme that breaks down fucose. Fucosidosis is an autosomal recessive lysosomal storage disease caused by defective alpha-L-fucosidase with accumulation of fucose in the tissues. Different phenotypes include clinical features such as neurologic deterioration, growth retardation, visceromegaly, and seizures in a severe early form; coarse facial features, angiokeratoma corporis diffusum, spasticity and delayed psychomotor development in a longer surviving form; and an unusual spondylometaphyseoepiphyseal dysplasia in yet another form.

Abbr

FUCA, Native

Alias

FUCA1; FUCA

Package

vial of 0.004 unit

Form

buffered aqueous solution, Solution in 20 mM Tris-HCl, pH 7.5, 25 mM NaCl

Enzyme Commission Number

EC 3.2.1.51

Activity

> 0.4 units/mg protein

CAS_No

9037-65-4

Unit Definition

One unit will release 1.0 μmole of fucose from 2′-fucosyllactose per min at pH 5.0 at 37°C

Storage

2-8°C

Pathway

Lysosome, organism-specific biosystem; Other glycan degradation, organism-specific biosystem

Function

alpha-L-fucosidase activity; carbohydrate binding

Synonyms

α-1,2-Fucosidase; alpha-L-fucosidase; Alpha-Fucosidase; FUCA1; FUCA; 9037-65-4

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Catalog	Product Name	EC No.	CAS No.	Source	Price
NATE-0260	Native Almond α (1-3,4) Fucosidase			Almond meal	Inquiry
NATE-0261	Native Bovine α (1-2,3,4,6) Fucosidase			Bovine kidney	Inquiry
NATE-0262	Native Xanthomonas sp. α-1→ (2,3,4) Fucosidase solution	EC 3.2.1.51	9037-65-4	Xanthomonas sp.	Inquiry
NATE-0263	Native Xanthomonas sp. α-1→ (3,4) Fucosidase solution	EC 3.2.1.51	9037-65-4	Xanthomonas sp.	Inquiry

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Project Description:

For research and industrial use only. Not intended for personal medicinal use. Certain food-grade products are suitable for formulation development in food and related applications.

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