PDE4A4B active from Human, Recombinant

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Cat No.

NATE-0524

Description

Human PDE4A4B, also known as PDE4A isoform 1 (GenBank Accession No. NM_001111307) amino acids 2-end with N-terminal GST-tag, MW= 124 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

Abbr

PDE4A, Recombinant (Human)

Alias

PDE4A10; PDE4A

Source

Baculovirus infected Sf9 cells

Species

Human

Applications

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Product Overview

Form

aqueous solution

Molecular Weight

mol wt 124 kDa

Purity

> 40% (SDS-PAGE)

Unit Definition

One unit is defined as the amount of enzyme that will convert 1 pmole of 3?, 5?-cAMP to 5?-AMP per min at 37°C.

Storage

−70°C

Pathway

DARPP-32 events, organism-specific biosystem; G Protein Signaling Pathways, organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; Morphine addiction, organism-specific biosystem; Morphine addiction, conserved biosystem; Myometrial Relaxation and Contraction Pathways, organism-specific biosystem

Function

3,5-cyclic-AMP phosphodiesterase activity; 3,5-cyclic-nucleotide phosphodiesterase activity; cAMP binding; drug binding; hydrolase activity; metal ion binding; phosphoric diester hydrolase activity

Synonyms

DPDE2; PDE46; phosphodiesterase 4A, cAMP-specific; PDE4A10; PDE4A

"Phosphodiesterase" Total Products Page

Enzymes

Catalog	Product Name	Source	Price
NATE-0519	Phosphodiesterase 2A FLAG tag active from Human, Recombinant	Baculovirus infected Sf9 cells	Inquiry
NATE-0520	Phosphodiesterase 2A active from Rat, Recombinant	Baculovirus infected Sf9 cells	Inquiry
NATE-0523	PDE4A10 active from Human, Recombinant	Baculovirus infected Sf9 cells	Inquiry
NATE-0527	Phosphodiesterase 5A1 from Human, Recombinant	Sf9 cells	Inquiry

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Our Products Cannot Be Used As Medicines Directly For Personal Use.

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