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Matrix Metalloproteinase 8

Official Full Name
Matrix Metalloproteinase 8
Background
Full-length recombinant human neutrophil pro-collagenase (MMP-8), latent form. Matrix metalloproteinase 8 (MMP-8), or neutrophil collagenase, degrades interstitial collagens, acting preferentially on collagen type I. Increased full-length MMP-8 protein was associated with infiltration into the skin of neutrophils, which are the major cell type that expresses MMP-8. MMP-8 is synthesized and stored in specific granules in neutrophil leukocytes. MMP-8 activity is therefore regulated by factors such as surface-bound ligands (IgG or complement components) that release it through degranulation.Once released and activated through proteolytic or oxidative mechanisms, MMP-8 plays a major role in the connective tissue turnover that accompanies inflammatory processes.
Synonyms
Neutrophil collagenase; EC 3.4.24.34; Matrix metalloproteinase-8; MMP-8; PMNL collagenase; PMNL-CL; HNC; CLG1

Catalog
ProductName
EC No.
CAS No.
Source
Price
CatalogEXWM-4316
EC No.EC 3.4.24.34
CAS No.9001-12-1
Source
CatalogNATE-0862
EC No.EC 3.4.24.34
CAS No.2593923
SourceE. coli
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