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XDH

Official Full Name
XDH
Background
Xanthine oxidoreductase (XOR) catalyzes the formation of uric acid from hypoxanthine and xanthine, last two steps of purine catabolism. The mammalian enzyme is synthesized as a xanthine dehydrogenase form (XDH, EC 1.17.1.4), which uses NAD as the electron acceptor, but is converted into an xanthine oxidase form (XO, EC 1.1.3.22) by reversible (through sulfhydryl group oxidation) or irreversible (proteolysis) manner. Since most industrial protocols of XOR purification includes proteolysis step, commercial XOR enzyme is available only as oxidase form unable to use NAD as a an electron acceptor.
Synonyms
xanthine dehydrogenase; NAD+-xanthine dehydrogenase; xanthine-NAD+ oxidoreductase; xanthine/NAD+ oxidoreductase; xanthine oxidoreductase; XDH; EC 1.17.1.4

Catalog
ProductName
EC No.
CAS No.
Source
Price
CatalogEXWM-1082
EC No.EC 1.17.1.4
CAS No.9054-84-6
Source
CatalogNATE-1065
EC No.EC 1.17.1.4
CAS No.9054-84-6
SourceBovine milk
CatalogNATE-1064
EC No.EC 1.17.1.4
CAS No.9054-84-6
SourceMicroorganism
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