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XDH

Official Full Name
XDH
Background
Xanthine oxidoreductase (XOR) catalyzes the formation of uric acid from hypoxanthine and xanthine, last two steps of purine catabolism. The mammalian enzyme is synthesized as a xanthine dehydrogenase form (XDH, EC 1.17.1.4), which uses NAD as the electron acceptor, but is converted into an xanthine oxidase form (XO, EC 1.1.3.22) by reversible (through sulfhydryl group oxidation) or irreversible (proteolysis) manner. Since most industrial protocols of XOR purification includes proteolysis step, commercial XOR enzyme is available only as oxidase form unable to use NAD as a an electron acceptor.
Synonyms
xanthine dehydrogenase; NAD+-xanthine dehydrogenase; xanthine-NAD+ oxidoreductase; xanthine/NAD+ oxidoreductase; xanthine oxidoreductase; XDH; EC 1.17.1.4
Catalog Product Name EC No. CAS No. Source Price
EXWM-1082 xanthine dehydrogenase EC 1.17.1.4 9054-84-6 Inquiry
NATE-1065 Native Xanthine Dehydrogenase from Bovine milk EC 1.17.1.4 9054-84-6 Bovine milk Inquiry
NATE-1064 Native Xanthine dehydrogenase from Microorganism EC 1.17.1.4 9054-84-6 Microorganism Inquiry